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Immunology and Infection

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JoVE Journal Immunology and Infection
Systemic Injection of Neural Stem/Progenitor Cells in Mice with Chronic EAE
 

Systemic Injection of Neural Stem/Progenitor Cells in Mice with Chronic EAE

Article DOI: 10.3791/51154-v • 09:24 min • April 15th, 2014
April 15th, 2014 •
1, 1, 1, 1, 1,2
1Department of Clinical Neurosciences, John Van Geest Centre for Brain Repair, University of Cambridge, UK, 2NIHR Biomedical Research Center, University of Cambridge, UK

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résumé
Automatic Translation

The transplantation of neural stem/progenitor cells (NPCs) holds great promises in regenerative neurology. The systemic delivery of NPCs has turned into effective, low invasive, and therapeutically very efficacious protocol to deliver stem cells in the brain and spinal cord of rodents and nonhuman primates affected by experimental chronic inflammatory damage of the central nervous system.

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Neural Stem/precursor Cells Transplantation Regenerative Neurology Brain Repair Stem Cell Therapies Cell Delivery Route Intraparenchymal Stem Cell Grafting Spinal Cord Injuries Parkinson's Disease Multiple Sclerosis Systemic NPC Delivery Chronic Inflammatory Damage Central Nervous System (CNS) NPC Pathotropism Cell Adhesion Molecules Inflammatory Cytokine Receptors Chemokine Receptors
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