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Fast Micro-iontophoresis of Glutamate and GABA: A Useful Tool to Investigate Synaptic Integration
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Neurosciences
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Journal JoVE Neurosciences
Fast Micro-iontophoresis of Glutamate and GABA: A Useful Tool to Investigate Synaptic Integration

Fast Micro-iontophoresis of Glutamate and GABA: A Useful Tool to Investigate Synaptic Integration

19,256 Views

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07:08 min

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July 31, 2013

DOI:

10.3791/50701-v

DOI:
10.3791/50701-v

•

07:08 min
July 31, 2013

•

6 Views
,
1NRW Research Group ‘Dendritic integration in the CNS’, Department of Epileptology,University of Bonn, 2Neuronal Networks Group,Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)

Summary

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In this article we introduce fast micro-iontophoresis of neurotransmitters as a technique to investigate integration of postsynaptic signals with high spatial and temporal precision.

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Micro-iontophoresisGlutamateGABASynaptic IntegrationDendritic TreeNeuronal OutputExcitatory InputsInhibitory InputsSpatial IntegrationTemporal IntegrationTwo-photon Scanning MicroscopeNeurotransmitter ReleasePresynapticPostsynaptic

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Cite this Article

Müller, C., Remy, S. Fast Micro-iontophoresis of Glutamate and GABA: A Useful Tool to Investigate Synaptic Integration. J. Vis. Exp. (77), e50701, doi:10.3791/50701 (2013).

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