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啮齿动物的中枢神经系统药物直接脑室交货
Journal JoVE
Neurosciences
This content is Free Access.
Journal JoVE Neurosciences
Direct Intraventricular Delivery of Drugs to the Rodent Central Nervous System
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啮齿动物的中枢神经系统药物直接脑室交货

58,980 Views

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14:55 min

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May 12, 2013

DOI:

10.3791/50326-v

DOI:
10.3791/50326-v

•

14:55 min
May 12, 2013

•

33 Views
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1Department of Neurology,Washington University in St. Louis School of Medicine

Summary

Automatically generated

我们描述了一种方法，目标通过植入导管或进行大剂量注射到在小鼠右侧脑室中枢神经系统的药物。我们特别专注于交付反义寡核苷酸。这种技术是很容易适应其他药物和大鼠。

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Cite this Article

DeVos, S. L., Miller, T. M. Direct Intraventricular Delivery of Drugs to the Rodent Central Nervous System. J. Vis. Exp. (75), e50326, doi:10.3791/50326 (2013).

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