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An Injury Paradigm to Investigate Central Nervous System Repair in Drosophila
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An Injury Paradigm to Investigate Central Nervous System Repair in Drosophila
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March 28, 2013
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An injury paradigm using the Drosophila larval ventral nerve cord to investigate central nervous system regeneration and repair is described. Stabbing followed by laser scanning confocal microscopy in time-lapse and fixed specimens, combined with quantitative analysis with purposefully developed software and genetics, are used to investigate the molecular mechanisms of CNS regeneration and repair.
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Kato, K., Hidalgo, A. An Injury Paradigm to Investigate Central Nervous System Repair in Drosophila. J. Vis. Exp. (73), e50306, doi:10.3791/50306 (2013).
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