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Assessment of Sensorimotor Function in Mouse Models of Parkinson’s Disease
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Assessment of Sensorimotor Function in Mouse Models of Parkinson’s Disease
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June 17, 2013
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In Parkinson's disease and movement disorders in general, sensitive and reliable behavioral assays are essential for testing novel potential therapeutics. Here, we describe a manageable battery of sensorimotor tests for mice that are sensitive to varying degrees of injury to the nigrostriatal system and useful for preclinical studies.
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Fleming, S. M., Ekhator, O. R., Ghisays, V. Assessment of Sensorimotor Function in Mouse Models of Parkinson's Disease. J. Vis. Exp. (76), e50303, doi:10.3791/50303 (2013).
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