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Immunologie et infection

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制备肿瘤抗原负载成熟树突状细胞免疫治疗

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Immunologie et infection

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Journal JoVE Immunologie et infection

Preparation of Tumor Antigen-loaded Mature Dendritic Cells for Immunotherapy

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制备肿瘤抗原负载成熟树突状细胞免疫治疗

18,043 Views

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08:40 min

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August 01, 2013

DOI:

10.3791/50085-v

DOI:

10.3791/50085-v

•

08:40 min

August 01, 2013

•

6 Views

Rachel Lubong Sabado¹, Elizabeth Miller², Meredith Spadaccia¹, Isabelita Vengco¹, Farah Hasan¹, Nina Bhardwaj¹

¹Cancer Institute,NYU Langone Medical Center, ²Infectious Diseases,NYU Langone Medical Center

Summary

用于产生在肿瘤免疫治疗中使用的大量的自体树突状细胞（DC）的最常用的方法进行说明。该方法使用的IL-4和GM-CSF分化的单核细胞的树突状。未成熟DC刺激才成熟，然后装入抗原注射到病人。

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