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Rapid Isolation of Viable Circulating Tumor Cells from Patient Blood Samples
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Rapid Isolation of Viable Circulating Tumor Cells from Patient Blood Samples
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June 15, 2012
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Circulating tumor cells are isolated from the blood of cancer patients without inflicting cellular damage. Isolation of tumor cells is accomplished using a bimolecular surface of E-selectin in addition to antibodies against epithelial markers. A nanotube coating specifically promotes cancer cell adhesion resulting in high capture purities.
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Hughes, A. D., Mattison, J., Powderly, J. D., Greene, B. T., King, M. R. Rapid Isolation of Viable Circulating Tumor Cells from Patient Blood Samples. J. Vis. Exp. (64), e4248, doi:10.3791/4248 (2012).
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