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JoVE Journal Neuroscience
Extinction Training During the Reconsolidation Window Prevents Recovery of Fear
 

Extinction Training During the Reconsolidation Window Prevents Recovery of Fear

Article DOI: 10.3791/3893-v • 11:17 min • August 24th, 2012
August 24th, 2012 •
1, 2, 3
1Departments of Psychiatry and Neuroscience, and Friedman Brain Institute, Mt. Sinai School of Medicine, 2Department of Psychology, New York University, 3Department of Psychology and Center for Neural Science, New York University

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résumé
Automatic Translation

Conditioned fear can be diminished through an inhibitory process called extinction, but can resurface under conditions such as the passage of time or exposure to stress. Our protocol presents a novel way of preventing fear recovery by introducing extinction during the reconsolidation window (the re-storage phase of a reactivated memory).

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Extinction Training Reconsolidation Window Fear Prevention Fear Recovery Pavlovian Fear-conditioning Paradigms Conditioned Stimulus Unconditioned Stimulus Conditioned Response Extinction Training Inhibitory Learning Fear Memory Spontaneous Recovery Of Fear Stress-induced Fear Contextual Fear Resurfacing Emotional Memory Modification Memory Reactivation
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