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Segmentation and Measurement of Fat Volumes in Murine Obesity Models Using X-ray Computed Tomography
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April 04, 2012
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Fat content analysis is routinely conducted in studies utilizing murine obesity models. Emerging methods in small animal CT imaging and analysis are providing for longitudinal detail rich fat content analysis. Here we detail step by step procedures for performing small animal CT imaging, analysis, and visualization.
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SegmentationMeasurementFat VolumesMurine Obesity ModelsX-ray Computed TomographyEnvironmental FactorsGenetic FactorsDisease MechanismsSmall Animal Models Of ObesityFat Content DataInvasive MethodsNon-invasive MethodsDual Energy X-ray Absorptiometry (DEXA)Magnetic Resonance (MR)Organ-specific Fat DistributionRegion-specific Fat DistributionLongitudinal AssessmentsSmall Animal CT Systems
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Sasser, T. A., Chapman, S. E., Li, S., Hudson, C., Orton, S. P., Diener, J. M., Gammon, S. T., Correcher, C., Leevy, W. M. Segmentation and Measurement of Fat Volumes in Murine Obesity Models Using X-ray Computed Tomography. J. Vis. Exp. (62), e3680, doi:10.3791/3680 (2012).
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