Journal
/
Médecine
/
Mouse Model of Middle Cerebral Artery Occlusion
Journal JoVE
Médecine
Author Produced
This content is Free Access.
Journal JoVE Médecine
Mouse Model of Middle Cerebral Artery Occlusion

Mouse Model of Middle Cerebral Artery Occlusion

76,371 Views

•

09:43 min

•

February 13, 2011

DOI:

10.3791/2761-v

DOI:
10.3791/2761-v

•

09:43 min
February 13, 2011

•

68 Views
, ,
1Department of Neurology,Ernest Gallo Clinic and Research Center, University of California, San Francisco, 2Department of Biological Sciences,Kent State University

Summary

Automatically generated

We demonstrate in the video a method for producing a middle cerebral artery occlusion in adult mice using an intraluminal monofilament. We also show how to evaluate the extent of cerebral infarction by 2,3,5-triphenyltetrazolium chloride (TTC) staining.

Explore More Videos

Mouse ModelMiddle Cerebral Artery Occlusion StrokeIschemic StrokeAnimal Stroke ModelsIntraluminal Monofilament ModelMCAOBlood Flow CessationBrain InfarctionReperfusionPermanent MCAOTransient MCAOCraniectomyCerebral IschemiaBrain Slices Staining

Read Article

Cite this Article

Chiang, T., Messing, R. O., Chou, W. Mouse Model of Middle Cerebral Artery Occlusion. J. Vis. Exp. (48), e2761, doi:10.3791/2761 (2011).

Download .ris file

Copy

Share Video

.

Copy