/
/
Magnetic Resonance Spectroscopy of live Drosophila melanogaster using Magic Angle Spinning
Un abonnement à JoVE est nécessaire pour voir ce contenu. Connectez-vous ou commencez votre essai gratuit.
Magnetic Resonance Spectroscopy of live Drosophila melanogaster using Magic Angle Spinning
12,392 Views
•
07:33 min
•
April 15, 2010
DOI:
1NMR Surgical Laboratory, Department of Surgery,Massachusetts General Hospital, Harvard Medical School, 2Shriners Burn Institute, 3Department of Radiology, Athinoula A. Martinos Center of Biomedical Imaging,Harvard Medical School, 4Molecular Surgery Laboratory, Department of Surgery,Massachusetts General Hospital, Harvard Medical School
Summary
Automatically generated
This technique enables the use of high-resolution magic angle spinning proton MR spectroscopy (HRMAS 1H-MRS) for molecular characterization of live Drosophila melanogaster with a conventional 14.1 tesla spectrometer equipped with an HRMAS probe.
Explore More Videos
Magnetic Resonance SpectroscopyLive Drosophila MelanogasterMagic Angle SpinningHigh-Resolution Magic Angle SpinningHRMAS Proton Magnetic Resonance Spectroscopy1H-MRSNon-destructive TechniqueSpectral Line-widthsHigh-resolution SpectraMetabolitesCellular ProcessesIn Vivo StudiesFruit Fly Drosophila MelanogasterGenetic OrganismBiological FunctionsSignaling PathwaysGenetics And PhysiologyIn Vivo HRMAS 1H-MRS Method14.1 TMR SpectrometerHRMAS ProbeMolecular CharacterizationDisease BiomarkersTherapeutic Development
Read Article
Cite this Article
Righi, V., Apidianakis, Y., Rahme, L. G., Tzika, A. A. Magnetic Resonance Spectroscopy of live Drosophila melanogaster using Magic Angle Spinning. J. Vis. Exp. (38), e1710, doi:10.3791/1710 (2010).
Copy