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Karakterisering av funksjonelt Associated miRNAs i glioblastom og deres Engineering i kunstige klynger for Gene Therapy
JoVE Revista
Genética
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JoVE Revista Genética
Characterization of Functionally Associated miRNAs in Glioblastoma and their Engineering into Artificial Clusters for Gene Therapy
DOI:

09:40 min

October 04, 2019

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Capítulos

  • 00:04Título
  • 01:19Induction of Cell Differentiation
  • 02:16Validation of miRNA Clusters by Stress-specific Challenges
  • 03:28Characterization of The Functional Convergence of Clustered miRNAs
  • 05:27Assembly of miRNA Modules into a Polycistronic Transgenic Cluster
  • 07:51Results: Functional miRNA Module and Transgene Processing
  • 08:40Conclusion

Summary

Traducción Automática

Beskrevet her er en protokoll for karakteriserer moduler av biologisk synergi miRNAs og deres forsamling i korte transgenes, som tillater samtidig overuttrykte for genterapi applikasjoner.

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