Short session (≤10 min) high intensity interval training (HIIT) is emerging as an alternative to longer exercise modalities, yet the shorter variants are rarely modeled in animal studies. Here, we describe a 10 min, 3 day a week, uphill treadmill HIIT protocol that enhances physical performance in male and female aged mice.
Seldeen, K. L., Redae, Y. Z., Thiyagarajan, R., Berman, R. N., Leiker, M. M., Troen, B. R. Short Session High Intensity Interval Training and Treadmill Assessment in Aged Mice. J. Vis. Exp. (144), e59138, doi:10.3791/59138 (2019).