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Inmunología y contagio
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Alternative In Vitro Methods for the Determination of Viral Capsid Structural Integrity
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Inmunología y contagio
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JoVE Revista Inmunología y contagio
Alternative In Vitro Methods for the Determination of Viral Capsid Structural Integrity

Alternative In Vitro Methods for the Determination of Viral Capsid Structural Integrity

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12:57 min

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November 16, 2017

DOI:

10.3791/56444-v

DOI:
10.3791/56444-v

•

12:57 min
November 16, 2017

•

2 Views
, ,
1Department of Food, Bioprocessing, and Nutrition Sciences,North Carolina State University, 2Department of Chemical and Biomolecular Engineering,North Carolina State University

Summary

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Routine detection methods utilizing viral genome amplification are limited by their inability to discriminate infectious from non-infectious particles. The purpose of this article is to provide detailed protocols for alternative methods to aid in discrimination of infectious norovirus particles using aptamer binding, dynamic light scattering, and transmission electron microscopy.

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Cite this Article

Moore, M. D., Mertens, B. S., Jaykus, L. Alternative In Vitro Methods for the Determination of Viral Capsid Structural Integrity. J. Vis. Exp. (129), e56444, doi:10.3791/56444 (2017).

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