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基于显微 CT 和荧光分子层析成像的多模态成像方法对博莱霉素诱导的小鼠肺纤维化的纵向评价
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Inmunología y contagio
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JoVE Revista Inmunología y contagio
A Multimodal Imaging Approach Based on Micro-CT and Fluorescence Molecular Tomography for Longitudinal Assessment of Bleomycin-Induced Lung Fibrosis in Mice
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基于显微 CT 和荧光分子层析成像的多模态成像方法对博莱霉素诱导的小鼠肺纤维化的纵向评价

11,171 Views

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07:38 min

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April 13, 2018

DOI:

10.3791/56443-v

DOI:
10.3791/56443-v

•

07:38 min
April 13, 2018

•

13 Views
, , , , , , , , ,
1Corporate Preclinical R&D,Chiesi Farmaceutici S.p.A., 2Department of Veterinary Science,University of Parma, 3Department of Molecular Genetics,Erasmus MC, 4Department of Molecular Genetics, Vascular Surgery, Radiation Oncology,Erasmus MC, 5Fluidda NV

Summary

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本文描述了一种基于微 CT 和荧光分子层析成像的无创多模成像方法, 用于对博莱霉素双气管灌注诱导的小鼠肺纤维化模型进行纵向评价。

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Micro-CTFluorescence Molecular TomographyLung FibrosisIPFMouse ModelLongitudinal AssessmentNon-invasive ImagingBleomycinProbe InjectionData AcquisitionImaging Cassette

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Ruscitti, F., Ravanetti, F., Donofrio, G., Ridwan, Y., van Heijningen, P., Essers, J., Villetti, G., Cacchioli, A., Vos, W., Stellari, F. F. A Multimodal Imaging Approach Based on Micro-CT and Fluorescence Molecular Tomography for Longitudinal Assessment of Bleomycin-Induced Lung Fibrosis in Mice. J. Vis. Exp. (134), e56443, doi:10.3791/56443 (2018).

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