A protocol is presented for X-ray crystallography using protein microcrystals. Two examples analyzing in vivo-grown microcrystals after purification or in cellulo are compared.
Boudes, M., Garriga, D., Coulibaly, F. Microcrystallography of Protein Crystals and In Cellulo Diffraction. J. Vis. Exp. (125), e55793, doi:10.3791/55793 (2017).