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慢性自身免疫性干眼鼠模型增加效应记忆T细胞在眼球组织
JoVE Revista
Inmunología y contagio
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JoVE Revista Inmunología y contagio
A Chronic Autoimmune Dry Eye Rat Model with Increase in Effector Memory T Cells in Eyeball Tissue
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慢性自身免疫性干眼鼠模型增加效应记忆T细胞在眼球组织

11,128 Views

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09:42 min

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June 07, 2017

DOI:

10.3791/55592-v

DOI:
10.3791/55592-v

•

09:42 min
June 07, 2017

•

6 Views
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1Singapore Eye Research Insitute, A Member of SingHealth, 2DUKE-National University of Singapore Medical School, 3Lee Kong Chian School of Medicine,Nanyang Technological University, 4Singapore National Eye Center, 5Yong Loo Lin School of Medicine,National University of Singapore

Summary

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该报告描述了通过用大鼠泪腺提取物，卵清蛋白和完全弗氏佐剂的乳液免疫在Lewis大鼠中诱导慢性实验性自身免疫性干眼的方法，随后将泪腺提取物和卵清蛋白注射入穹隆结膜下和泪腺六周后。

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Cite this Article

Hou, A., Bose, T., Chandy, K. G., Tong, L. A Chronic Autoimmune Dry Eye Rat Model with Increase in Effector Memory T Cells in Eyeball Tissue. J. Vis. Exp. (124), e55592, doi:10.3791/55592 (2017).

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