Journal
/
Biología del desarrollo
/
Large-scale Scanning Transmission Electron Microscopy (Nanotomy) of Healthy and Injured Zebrafish Brain
JoVE Revista
Biología del desarrollo
This content is Free Access.
JoVE Revista Biología del desarrollo
Large-scale Scanning Transmission Electron Microscopy (Nanotomy) of Healthy and Injured Zebrafish Brain

Large-scale Scanning Transmission Electron Microscopy (Nanotomy) of Healthy and Injured Zebrafish Brain

10,898 Views

•

10:09 min

•

May 25, 2016

DOI:

10.3791/53635-v

DOI:
10.3791/53635-v

•

10:09 min
May 25, 2016

•

7 Views
, , , ,
1Cell Biology,UMC Groningen, 2Clinical Genetics,Erasmus MC Rotterdam

Summary

Automatically generated

Large-scale 2D electron microscopy (EM), or nanotomy, is the tissue-wide application of nanoscale resolution EM. Here we describe a universal method for nanotomy applied to investigate the zebrafish larval brain in health and upon non-invasive brain injury.

Explore More Videos

AI WriterAI MicroscopyNanotomyLarge-scale Electron MicroscopyBrain DegenerationZebrafishNeurodegenerative DiseaseOpen-access DataQuantitative Analysis

Read Article

Cite this Article

Kuipers, J., Kalicharan, R. D., Wolters, A. H. G., van Ham, T. J., Giepmans, B. N. Large-scale Scanning Transmission Electron Microscopy (Nanotomy) of Healthy and Injured Zebrafish Brain. J. Vis. Exp. (111), e53635, doi:10.3791/53635 (2016).

Download .ris file

Copy

Share Video

.

Copy