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Dorsal Root Ganglia Neurons and Differentiated Adipose-derived Stem Cells
 

Dorsal Root Ganglia Neurons and Differentiated Adipose-derived Stem Cells: An In Vitro Co-culture Model to Study Peripheral Nerve Regeneration

Article DOI: 10.3791/52543-v • 09:17 min • February 26th, 2015
February 26th, 2015 •
1, 2, 2,3
1Centre for Neuroprosthesis, EPFL | STI | IMT/IBI | LSBI, 2Blond McIndoe Research Laboratories, Institute of Inflammation & Repair, The University of Manchester, 3University Hospital of South Manchester

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Dorsal root ganglia (DRG) are structures containing the sensory neurons of the peripheral nervous system. When dissociated, they can be co-cultured with SC-like adipose-derived stem cells (ASC), providing a valuable model to study in vitro nerve regeneration and myelination, mimicking the in vivo environment at the injury site.

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Keywords: Dorsal Root Ganglia DRG Neurons Adipose-derived Stem Cells ASC Schwann Cells Peripheral Nerve Regeneration Co-culture In Vitro Model
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