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Unilateral Pyramidotomy of the Corticospinal Tract in Rats for Assessment of Neuroplasticity-inducing Therapies
JoVE Revista
Neurociencias
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JoVE Revista Neurociencias
Unilateral Pyramidotomy of the Corticospinal Tract in Rats for Assessment of Neuroplasticity-inducing Therapies
DOI:

08:41 min

December 15, 2014

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Capítulos

  • 00:05Título
  • 01:08Preparing for Surgery
  • 02:16Exposing the Pyramid
  • 04:22Performing the Pyramidotomy
  • 06:50Results: Post-pyramidotomy Functional Deficit and Histology Analysis
  • 08:21Conclusion

Summary

Traducción Automática

The corticospinal tract, one of the major sensorimotor tracts, can be lesioned unilaterally in the rodent brainstem in order to test neuroplasticity-inducing therapies for the central nervous system. This surgical procedure (“pyramidotomy”) and postoperative assessments are described in this protocol.

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