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Chapters
- 00:05Title
- 01:08Preparing for Surgery
- 02:16Exposing the Pyramid
- 04:22Performing the Pyramidotomy
- 06:50Results: Post-pyramidotomy Functional Deficit and Histology Analysis
- 08:21Conclusion
The corticospinal tract, one of the major sensorimotor tracts, can be lesioned unilaterally in the rodent brainstem in order to test neuroplasticity-inducing therapies for the central nervous system. This surgical procedure (“pyramidotomy”) and postoperative assessments are described in this protocol.
