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April 16, 2013
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一个特异和敏感的方法来深入了解糖脂抗原的免疫器官和细胞的表达谱。该方法利用离子阱质谱可以逐步碎裂的糖脂分子结构分析，比较，化学合成的标准。
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Mass Spectrometric AnalysisGlycosphingolipid AntigensGSL’sGlycoconjugate BiomacromoleculesStructural InformationEmbryonic DevelopmentSignal TransductionImmune Receptor RecognitionSugar MoietiesIsomersLipid MoietiesFatty Acyl Chain LengthUnsaturationHydroxylationCarbohydrate PortionCeramide PortionTri-hexosylceramidesGlobotriaosylceramide (Galα4Galβ4Glcβ1Cer)Isoglobotriaosylceramide (Galα3Galβ4Glcβ1Cer)Molecular MassesSugar LinkagesBiological FunctionsModification Of Ceramide PartAlpha-galactosylceramideCytokine Secretion ProfilesInvariant NKT CellsCancer ModelsAutoimmune DiseasesStructural Analysis Of IsomersImmune Organs And Cells
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Yin, A. B., Hawke, D., Zhou, D. Mass Spectrometric Analysis of Glycosphingolipid Antigens. J. Vis. Exp. (74), e4224, doi:10.3791/4224 (2013).
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