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November 03, 2011
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计算机准则的基础结构和功能的蛋白质使用的I - TASSER管道的特性描述。开始，从查询蛋白质序列生成三维模型使用多个线程的路线和迭代结构装配模拟。此后绘制功能的推论是基于匹配与已知的结构和功能的蛋白质。
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ProtocolComputer-basedProtein StructureFunction PredictionGenome Sequencing ProjectsProtein SequenceStructure And Function KnowledgeExperimental MethodsComputational ModelingI-TASSER ServerSecondary Structure PredictionSolvent Accessibility PredictionHomologous Template ProteinsStructure AlignmentsTertiary Structural ModelsStructure-based Functional AnnotationsConfidence ScoreEnd UsersUser-specified Inter-residue DistanceContact MapsI-TASSER ModelingTemplate ProteinsStructure Assembly Simulations
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Roy, A., Xu, D., Poisson, J., Zhang, Y. A Protocol for Computer-Based Protein Structure and Function Prediction. J. Vis. Exp. (57), e3259, doi:10.3791/3259 (2011).
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