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생물학적 장벽의 침투 강화를 위한 순환 세포 침투 펩타이드의 구성
JoVE Journal
Chemie
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JoVE Journal Chemie
Construction of Cyclic Cell-Penetrating Peptides for Enhanced Penetration of Biological Barriers
DOI:

10:12 min

September 19, 2022

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Kapitel

  • 00:04Introduction
  • 01:10Equipment Preparation
  • 01:44Synthesis of FITC‐Labeled Linear R8 Peptide and FITC‐Labeled Stapled R8 Peptide
  • 05:49Exploration of the Cell‐to‐Cell Penetration of the Peptides Using Transwell Models
  • 07:06Results: Synthesis of FITC‐R8 and FITC‐sR8‐4 Using Solid‐Phase Peptide Synthesis and Evaluation of Their Trans‐Barrier Permeability
  • 09:06Conclusion

Summary

Automatische Übersetzung

이 프로토콜은 방향족 가교를 갖는 고리형 세포 침투 펩타이드의 합성과 생물학적 장벽을 통한 투과성 평가를 설명합니다.

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