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Deciphering Molecular Mechanism of Histone Assembly by DNA Curtain Technique
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March 09, 2022
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DNA curtain, a high-throughput single-molecule imaging technique, provides a platform for real-time visualization of diverse protein-DNA interactions. The present protocol utilizes the DNA curtain technique to investigate the biological role and molecular mechanism of Abo1, a Schizosaccharomyces pombe bromodomain-containing AAA+ ATPase.
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Kang, Y., Bae, S., An, S., Lee, J. Y. Deciphering Molecular Mechanism of Histone Assembly by DNA Curtain Technique. J. Vis. Exp. (181), e63501, doi:10.3791/63501 (2022).
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