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Systematic Scoring Analysis for Intestinal Inflammation in a Murine Dextran Sodium Sulfate-Induced Colitis Model
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Systematic Scoring Analysis for Intestinal Inflammation in a Murine Dextran Sodium Sulfate-Induced Colitis Model
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February 14, 2021
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Systematic scoring of intestinal inflammation using a free computer-assisted system is a powerful tool to quantitatively compare histopathological changes in colitis models characterized by the presence of ulcers and inflammatory changes. Histological colitis score evaluation strengthens clinical observations and facilitates data interpretation.
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Keyword Extraction:Systematic Scoring AnalysisIntestinal InflammationMurine Dextran Sodium Sulfate-induced Colitis ModelMucosal InjuryHistological InterpretationQuantitative AnalysisIntestinesMiceColitisEuthanized MouseDissecting PadAbdominal SkinPeritoneumLarge IntestinePelvic BoneColonPBSWestern BlotPCRImmunofluorescence MicroscopyNeutral Buffered Formalin Solution
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Garcia-Hernandez, V., Neumann, P., Koch, S., Lyons, R., Nusrat, A., Parkos, C. A. Systematic Scoring Analysis for Intestinal Inflammation in a Murine Dextran Sodium Sulfate-Induced Colitis Model. J. Vis. Exp. (168), e62135, doi:10.3791/62135 (2021).
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