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Eksponering for cigaretrøg hos mus ved hjælp af et inhalationssystem til hele kroppen
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1Program in Immunology,Baylor College of Medicine, 2Department of Pediatrics, Section of Infectious Diseases,Baylor College of Medicine, 3Department of Medicine – Immunology Allergy and Rheumatology,Baylor College of Medicine, 4Department of Medicine, Pulmonary, Critical Care, Sleep Medicine,Baylor College of Medicine, 5Department of Pathology and Immunology,Baylor College of Medicine, 6Department of Pediatrics, Research and Department of Epigenetics and Molecular Carcinogenesis,The University of Texas MD Anderson Cancer Center, 7Division of Pulmonary and Critical Care Medicine,The First Affiliated Hospital of Sun Yat-sen University, 8Center for Translational Research on Inflammatory Diseases (CTRID),Michael E. DeBakey VA Medical Center
Kapitel
- 00:04Introduction
- 00:34Setting Pressure and Airflow
- 01:46Cigarette Smoke Treatment
- 03:37Results: CS-mediated lnduction of Airway lnflammation and Lung Emphysematous Changes in Mice
- 05:14Conclusion
Denne protokol demonstrerer undersøgelsen af de patofysiologiske virkninger af cigaretrøg (CS) med et helkropsinhalationssystem (WBI) (WBIS), der er bygget internt. Dette system kan udsætte dyr for CS under kontrollerede repeterbare betingelser for forskning i CS-medierede virkninger på lungeafysem og hæmatopoiesis.
