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Assisted Selection of Biomarkers by Linear Discriminant Analysis Effect Size (LEfSe) in Microbiome Data
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May 16, 2022
DOI:
1Marine Resources Research Centre,Tianjin Research Institute for Water Transport Engineering, M.O.T., 2Key Laboratory of Regional Energy Systems Optimization, Ministry of Education, College of Environmental Science and Engineering,North China Electric Power University, 3School of Environmental Science and Engineering,Huazhong University of Science and Technology
Summary
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LEfSe (LDA Effect Size) is a tool for high-dimensional biomarker mining to identify genomic features (such as genes, pathways, and taxonomies) that significantly characterize two or more groups in microbiome data.
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Chang, F., He, S., Dang, C. Assisted Selection of Biomarkers by Linear Discriminant Analysis Effect Size (LEfSe) in Microbiome Data. J. Vis. Exp. (183), e61715, doi:10.3791/61715 (2022).
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