Journal
/
Chemie
/
Synthesis of Aptamer-PEI-g-PEG Modified Gold Nanoparticles Loaded with Doxorubicin for Targeted Drug Delivery
JoVE Journal
Chemie
Zum Anzeigen dieser Inhalte ist ein JoVE-Abonnement erforderlich.  Melden Sie sich an oder starten Sie Ihre kostenlose Testversion.
JoVE Journal Chemie
Synthesis of Aptamer-PEI-g-PEG Modified Gold Nanoparticles Loaded with Doxorubicin for Targeted Drug Delivery

Synthesis of Aptamer-PEI-g-PEG Modified Gold Nanoparticles Loaded with Doxorubicin for Targeted Drug Delivery

5,616 Views

•

09:09 min

•

June 23, 2020

DOI:

10.3791/61139-v

DOI:
10.3791/61139-v

•

09:09 min
June 23, 2020

•

6 Views
, , , , , ,
1College of Life Sciences,Xinyang Normal University, 2Department of Imaging & Pathology, University of Leuven and Oral & Maxillofacial Surgery,University Hospitals Leuven, 3Analysis & Testing Center,Xinyang Normal University

Summary

Automatically generated

In this protocol, doxorubicin-loaded AS1411-g-PEI-g-PEG modified gold nanoparticles are synthesized via three-step amide reactions. Then, doxorubicin is loaded and delivered to target cancer cells for cancer therapy.

Explore More Videos

DoxorubicinDrug DeliveryGold NanoparticlesAptamerPEI-g-PEGCT-PEGTargeted Drug DeliveryCancer TreatmentDrug ResistanceToxicity

Read Article

Cite this Article

Nie, L., Sun, S., Sun, M., Zhou, Q., Zhang, Z., Zheng, L., Wang, L. Synthesis of Aptamer-PEI-g-PEG Modified Gold Nanoparticles Loaded with Doxorubicin for Targeted Drug Delivery. J. Vis. Exp. (160), e61139, doi:10.3791/61139 (2020).

Download .ris file

Copy

Share Video

.

Copy