Journal
/
Chemie
/
Mass Spectrometry-Guided Genome Mining as a Tool to Uncover Novel Natural Products
JoVE Journal
Chemie
Zum Anzeigen dieser Inhalte ist ein JoVE-Abonnement erforderlich.  Melden Sie sich an oder starten Sie Ihre kostenlose Testversion.
JoVE Journal Chemie
Mass Spectrometry-Guided Genome Mining as a Tool to Uncover Novel Natural Products

Mass Spectrometry-Guided Genome Mining as a Tool to Uncover Novel Natural Products

10,596 Views

•

11:13 min

•

March 12, 2020

DOI:

10.3791/60825-v

DOI:
10.3791/60825-v

•

11:13 min
March 12, 2020

•

14 Views
, , ,
1Department of Organic Chemistry, Institute of Chemistry,University of Campinas (UNICAMP), 2Center for Natural and Human Sciences,Federal University of ABC (UFABC)

Summary

Automatically generated

A mass spectrometry-guided genome mining protocol is established and described here. It is based on genome sequence information and LC-MS/MS analysis and aims to facilitate identification of molecules from complex microbial and plant extracts.

Explore More Videos

Mass SpectrometryGenome MiningNatural Product DiscoveryMolecular NetworkingWhole Genome SequencingGenotype-to-chemotypeBiosynthetic ClustersSecondary MetabolismGNPSStreptomycesFungiPlants

Read Article

Cite this Article

Sigrist, R., Paulo, B. S., Angolini, C. F. F., De Oliveira, L. G. Mass Spectrometry-Guided Genome Mining as a Tool to Uncover Novel Natural Products. J. Vis. Exp. (157), e60825, doi:10.3791/60825 (2020).

Download .ris file

Copy

Share Video

.

Copy