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A Revised Surgical Approach to Induce Endolymphatic Hydrops in the Guinea Pig
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JoVE Journal Neurowissenschaften
A Revised Surgical Approach to Induce Endolymphatic Hydrops in the Guinea Pig

A Revised Surgical Approach to Induce Endolymphatic Hydrops in the Guinea Pig

5,919 Views

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06:05 min

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June 04, 2020

DOI:

10.3791/60597-v

DOI:
10.3791/60597-v

•

06:05 min
June 04, 2020

•

4 Views
, , ,
1Department of Otolaryngology, Head and Neck Surgery,Washington University School of Medicine in St. Louis

Summary

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This article demonstrates an extradural approach to obliterate the guinea pig endolymphatic sac and injure the endolymphatic duct with a fine pick in order to induce experimental endolymphatic hydrops.

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Valenzuela, C. V., Lee, C., Buchman, C. A., Lichtenhan, J. T. A Revised Surgical Approach to Induce Endolymphatic Hydrops in the Guinea Pig. J. Vis. Exp. (160), e60597, doi:10.3791/60597 (2020).

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