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Thoracic Spinal Cord Hemisection Surgery and Open-Field Locomotor Assessment in the Rat
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Thoracic Spinal Cord Hemisection Surgery and Open-Field Locomotor Assessment in the Rat
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June 26, 2019
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The rat thoracic spinal hemisection is a valuable and reproducible model of unilateral spinal cord injury to investigate the neural mechanisms of locomotor recovery and treatment efficacy. This article includes a detailed step-by-step guide to perform the hemisection procedure and to assess locomotor performance in an open-field arena.
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Brown, A. R., Martinez, M. Thoracic Spinal Cord Hemisection Surgery and Open-Field Locomotor Assessment in the Rat. J. Vis. Exp. (148), e59738, doi:10.3791/59738 (2019).
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