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Journal / Developmental Biology / Direct Lineage Reprogramming of Adult Mouse…
JoVE Journal
Developmental Biology

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JoVE Journal Developmental Biology
Direct Lineage Reprogramming of Adult Mouse Fibroblast to Erythroid Progenitors
 

Direct Lineage Reprogramming of Adult Mouse Fibroblast to Erythroid Progenitors

Article DOI: 10.3791/58464-v • 11:46 min • December 14th, 2018
December 14th, 2018 •
1, 1, 1, 1, 1
1Department of Molecular Medicine and Gene Therapy, Lund University

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Summary
Automatic Translation

Here we present our protocol for producing induced erythroid progenitors (iEPs) from mouse adult fibroblasts using transcription factor-driven direct lineage reprogramming (DLR).

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Keywords: Direct Lineage Reprogramming Fibroblasts Erythroid Progenitor Cells Transcriptional Regulation In Vitro Tail-tip Fibroblasts Transfusion Medicine Chromatin Modifications Gene Expression Changes
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