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Journal / Medicine / In vitro Enrichment of Ovarian Cancer…
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In vitro Enrichment of Ovarian Cancer Tumor-initiating Cells
 

In vitro Enrichment of Ovarian Cancer Tumor-initiating Cells

Article DOI: 10.3791/52446-v • 11:37 min • February 18th, 2015
February 18th, 2015 •
1, 1, 1
1Women's Malignancies Branch, National Cancer Institute

Kapitel

Summary
Automatic Translation

Tumor-initiating cells (TICs) may represent a viable therapeutic target for the treatment of ovarian cancer, a highly recurrent and fatal disease. We present a protocol for culture conditions that enrich for this highly tumorigenic population of cells.

Tags

In Vitro Enrichment Ovarian Cancer Tumor-initiating Cells Self-renewing Differentiation Capacity Tumor Formation Tumor Progression Clinically Favorable Therapies Disease Biology Culture Conditions Cell Lines Low Attachment Plate Serum Free Media Growth Factors Stem Cell Markers (CD133 And ALDH Activity) Tumorigenicity Floater Cells Low Adherence Spheres Putative Stem Cell Markers Signaling Pathways
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