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개발<em> 체외</em의 상호 작용을 연구> 모델 시스템<em> 에쿠스</em><em> caballus</em높은 친 화성 수용체 FcεRI에>의 IgE
JoVE Journal
Immunologie und Infektion
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JoVE Journal Immunologie und Infektion
Development of an in vitro model system for studying the interaction of Equus caballus IgE with its high-affinity receptor FcεRI

개발<em> 체외</em의 상호 작용을 연구> 모델 시스템<em> 에쿠스</em><em> caballus</em높은 친 화성 수용체 FcεRI에>의 IgE

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07:31 min

November 01, 2014

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07:31 min
November 01, 2014

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Summary

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The current study describes the development and applications of a genetically engineered assay system based on the transfection of rat basophilic leukemia cells with the equine FcεRIα gene. Transfected cells express a functional receptor where the release of mediators of the allergic response can be activated by IgE and antigen.

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