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Induction of Adhesion-dependent Signals Using Low-intensity Ultrasound
JoVE Journal
Biotechnik
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JoVE Journal Biotechnik
Induction of Adhesion-dependent Signals Using Low-intensity Ultrasound

Induction of Adhesion-dependent Signals Using Low-intensity Ultrasound

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08:51 min

May 08, 2012

DOI:

08:51 min
May 08, 2012

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Summary

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This protocol describes the stimulation of cultured fibroblasts with low-intensity pulsed ultrasound, which drives focal adhesion formation and Rac1 activation by mimicking engagement of the transmembrane matrix receptor, syndecan-4. This approach allows investigation of a successful clinical technique at the cellular level, thereby providing opportunities for refinement of the therapy.

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