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Methods for Intravenous Self Administration in a Mouse Model
JoVE Journal
Neurowissenschaften
Author Produced
This content is Free Access.
JoVE Journal Neurowissenschaften
Methods for Intravenous Self Administration in a Mouse Model
DOI:

12:09 min

December 08, 2012

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Kapitel

  • 00:00Titel
  • 00:51Preparation of Catheter Accessories
  • 02:17Catheter Preparation
  • 02:43Anesthesia
  • 03:19Surgery
  • 11:15Recovery
  • 11:27Conclusion

Summary

Automatische Übersetzung

The intravenous self-administration (IVSA) paradigm is considered to be the gold standard in examining the reinforcing properties of drugs of abuse in rodents. This manuscript outlines the experimental procedures and surgical techniques necessary to obtain reliable IVSA data. In particular, meticulous catheter implantation and maintenance are highlighted.

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