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Immunologie und Infektion
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Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs
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Immunologie und Infektion
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JoVE Journal Immunologie und Infektion
Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs

Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs

DOI:
10.3791/3533-v

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11:36 min

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April 21, 2012

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, , , , , , , , , , , , , ,
1Program for the Study and Control of Tropical Diseases -PECET-School of Medicine,University of Antioquia, 2School of Agrarian Sciences,University of Antioquia

Kapitel

  • 00:05Titel
  • 00:15Introduction
  • 00:56Technical Procedure
  • 09:43Discussion and Results

Summary

Automatische Übersetzung

Automatische Übersetzung

Optimization of the experimental hamster model for cutaneous leishmaniasis by intradermal injection of Leishmania promastigotes at the dorsal skin. This approach is useful during inoculation, follow-up, characterization of lesions, application of treatments and obtaining of clinical samples. Locomotion, search for food and water, play and social activities are preserved.

Tags

Cutaneous LeishmaniasisDorsal SkinHamstersScreeningAntileishmanial DrugsInoculationUlcerLesion Size MeasurementHamster Model OptimizationGolden HamstersIntradermal InjectionPromastigotesLeishmania SpeciesProgression Of LesionsInfection EvaluationChronic LesionsClinical EvolutionIndurationsUlcersTreatment ApplicationClinical Samples

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