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Immunology and Infection

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JoVE Journal Immunology and Infection
Protocols for Vaginal Inoculation and Sample Collection in the Experimental Mouse Model of Candida vaginitis
 

Protocols for Vaginal Inoculation and Sample Collection in the Experimental Mouse Model of Candida vaginitis

Article DOI: 10.3791/3382-v • 07:58 min • December 8th, 2011
December 8th, 2011 •
1, 1
1Louisiana State University Health Sciences Center

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Summary
Automatic Translation

Key techniques to be used in the evaluation of Candida vaginitis in an experimental animal model are described. The methods will allow rapid collection of vaginal specimens and lymphocytes from draining lumbar lymph nodes. These techniques could give rise to mouse models of other diseases in the female lower genital tract.

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Vaginal Inoculation Sample Collection Experimental Mouse Model Candida Vaginitis Vulvovaginal Candidiasis Candida Species Fungal Infection Lower Female Genital Tract Predisposing Factors Antibiotic Usage Uncontrolled Diabetes Reproductive Hormone Levels Pregnancy Oral Contraceptives Hormone Replacement Therapies Recurrent VVC Experimental Mouse Model Of VVC Pathogenesis Mucosal Host Response Antifungal Therapies Pseudoestrus Candida Colonization/infection
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