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GABA-activated Single-channel and Tonic Currents in Rat Brain Slices
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GABA-activated Single-channel and Tonic Currents in Rat Brain Slices
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July 17, 2011
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We use the patch-clamp technique to measure GABA-activated single-channel currents (GABAA channels, GABAA receptors) and the synaptic and tonic currents they generate in neurons. Activation of the channels decreases neuronal excitability in health and disease 1,2,3,4.
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Cite this Article
Jin, Z., Jin, Y., Birnir, B. GABA-activated Single-channel and Tonic Currents in Rat Brain Slices. J. Vis. Exp. (53), e2858, doi:10.3791/2858 (2011).
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