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Immunologie und Infektion

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HLA-Ig Basierend Artificial Antigen-präsentierende Zellen für eine effiziente Ex vivo Erweiterung des menschlichen CTL

JoVE Journal
Immunologie und Infektion

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JoVE Journal Immunologie und Infektion

HLA-Ig Based Artificial Antigen Presenting Cells for Efficient ex vivo Expansion of Human CTL

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HLA-Ig Basierend Artificial Antigen-präsentierende Zellen für eine effiziente Ex vivo Erweiterung des menschlichen CTL

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07:18 min

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April 11, 2011

DOI:

DOI:

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07:18 min

April 11, 2011

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Yen-Ling Chiu², Jonathan P. Schneck⁴, Mathias Oelke⁴

¹Immunology Graduate Program,Johns Hopkins University, ²Department of Internal Medicine,Far-Eastern Memorial Hospital, ³Department of Pathology,Johns Hopkins University, ⁴Institute of Cell Engineering,Johns Hopkins University

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HLA-Ig Artificial Antigen Presenting Cells Ex Vivo Expansion Human CTL Effector Function Immune Microenvironment Autologous Antigen Presenting Cells Tolerize Anergize Adoptive Immunotherapy Cancer Virus Infections CMV-specific CTL Immunocompromised Allogeneic Bone Marrow Transplant Patients Anti-CMV Immunity Melanoma Cost And Technical Limitations Autologous DC Leukocytes

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