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HLA-Ig Based Artificial Antigen Presenting Cells for Efficient ex vivo Expansion of Human CTL
JoVE 杂志
免疫与感染
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JoVE 杂志 免疫与感染
HLA-Ig Based Artificial Antigen Presenting Cells for Efficient ex vivo Expansion of Human CTL

HLA-Ig Based Artificial Antigen Presenting Cells for Efficient ex vivo Expansion of Human CTL

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07:18 min

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April 11, 2011

DOI:

10.3791/2801-v

DOI:
10.3791/2801-v

•

07:18 min
April 11, 2011

•

1 Views
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1Immunology Graduate Program,Johns Hopkins University, 2Department of Internal Medicine,Far-Eastern Memorial Hospital, 3Department of Pathology,Johns Hopkins University, 4Institute of Cell Engineering,Johns Hopkins University

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HLA-IgArtificial Antigen Presenting CellsEx Vivo ExpansionHuman CTLEffector FunctionImmune MicroenvironmentAutologous Antigen Presenting CellsTolerizeAnergizeAdoptive ImmunotherapyCancerVirus InfectionsCMV-specific CTLImmunocompromised Allogeneic Bone Marrow Transplant PatientsAnti-CMV ImmunityMelanomaCost And Technical LimitationsAutologous DCLeukocytes

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Chiu, Y., Schneck, J. P., Oelke, M. HLA-Ig Based Artificial Antigen Presenting Cells for Efficient ex vivo Expansion of Human CTL. J. Vis. Exp. (50), e2801, doi:10.3791/2801 (2011).

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