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Elastomeric PGS Scaffolds in Arterial Tissue Engineering
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April 08, 2011
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Elastomeric PGS scaffolds with vascular smooth muscle cells cultured in a pulsatile flow bioreactor may lead to promising small-diameter arterial constructs with native ECM production in a relatively short culture period.
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Elastomeric PGS ScaffoldsCardiovascular DiseaseMortalityCoronary Artery DiseaseBypass SurgeryAutologous VesselsAllograftsSynthetic GraftsInner Diameter Of ArteriesLimited ApplicationsThrombotic ComplicationsCompliance MismatchLate Intimal HyperplasiaSmall-diameter Arterial ConstructsNonthrombogenicRobustCompliantTri-lamellar StructureMechanical PropertiesBurst PressureCollagen ProductionElastin ProductionComplianceGraft FailureElastomeric BiomaterialMechanical Conditioning
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Lee, K., Wang, Y. Elastomeric PGS Scaffolds in Arterial Tissue Engineering. J. Vis. Exp. (50), e2691, doi:10.3791/2691 (2011).
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