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原位Xenografting人类荧光素酶标记的恶性外周神经鞘瘤细胞在体内测试候选治疗药物
JoVE Journal
Medizin
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JoVE Journal Medizin
Orthotopic Xenografting of Human Luciferase-Tagged Malignant Peripheral Nerve Sheath Tumor Cells for in vivo Testing of Candidate Therapeutic Agents
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原位Xenografting人类荧光素酶标记的恶性外周神经鞘瘤细胞在体内测试候选治疗药物

18,312 Views

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07:10 min

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March 07, 2011

DOI:

10.3791/2558-v

DOI:
10.3791/2558-v

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07:10 min
March 07, 2011

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1 Views
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1Department of Pathology,University of Alabama at Birmingham – UAB, 2Department of Radiology,University of Alabama at Birmingham – UAB, 3Department of Cell Biology and Neurobiology,University of Alabama at Birmingham – UAB

Summary

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一种可靠荧光素酶标记的人类恶性外周神经鞘肿瘤细胞移植到免疫缺陷小鼠坐骨神经的方法是描述。利用生物发光成像显示肿瘤移植和动物为研究组随机分离的标准进行了适当的建立进行了讨论。

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Cite this Article

Turk, A. N., Byer, S. J., Zinn, K. R., Carroll, S. L. Orthotopic Xenografting of Human Luciferase-Tagged Malignant Peripheral Nerve Sheath Tumor Cells for in vivo Testing of Candidate Therapeutic Agents. J. Vis. Exp. (49), e2558, doi:10.3791/2558 (2011).

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