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Journal / Neuroscience / C. elegans Positive Butanone Learning,…
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Neuroscience

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JoVE Journal Neuroscience
C. elegans Positive Butanone Learning, Short-term, and Long-term Associative Memory Assays
 

C. elegans Positive Butanone Learning, Short-term, and Long-term Associative Memory Assays

Article DOI: 10.3791/2490-v • 09:58 min • March 11th, 2011
March 11th, 2011 •
1, 2, 1, 1, 1, 1
1Department of Molecular Biology, Lewis-Sigler Institute for Integrative Genomics, Princeton University, 2Lewis-Sigler Institute for Integrative Genomics, Princeton University

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Summary
Automatic Translation

Here we describe methods to test C. elegans associative learning and short- and long-term associative memory. These population assays employ the worms abilities to chemotax toward volatile odorants, and form positive associations upon pairing food with the chemoattractant butanone. Increasing the number of conditioning periods induces long-term memory.

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C. Elegans Positive Butanone Learning Short-term Memory Long-term Memory Associative Memory Assays Aversive Olfactory Learning Paradigm AWC Neuron-sensed Volatile Chemoattractant Butanone Chemotactic Index Population Chemotaxis Assay Learning Index Food And Butanone Pairing Massed Training Spaced Training CAMP Response Element
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