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Efficient Adeno-Associated Virus Vector Production Using a Cell Factory Platform
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Author Spotlight: Advancing Gene Therapy Research with High-Titer Adeno-Associated Virus Vector Production
JoVE 杂志
生物工程
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JoVE 杂志 生物工程
A Streamlined and Standardized Procedure for Generating High-Titer, High-Quality Adeno-Associated Virus Vectors Utilizing a Cell Factory Platform

Author Spotlight: Advancing Gene Therapy Research with High-Titer Adeno-Associated Virus Vector Production

Efficient Adeno-Associated Virus Vector Production Using a Cell Factory Platform

DOI:
10.3791/66741-v

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01:52 min

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May 03, 2024

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, , , , ,
1Division of Pediatric Surgery, Department of Surgery, Children’s Hospital of Pittsburgh,University of Pittsburgh School of Medicine, 2North Allegheny High School, 3Wright State University Boonshoft School of Medicine, 4College of Engineering,University of Michigan

Tags

Adeno-associated VirusAAV VectorsCell Factory PlatformCell StacksHEK293T CellsPurificationYieldPurityPolyethylene GlycolIodixanol GradientSDS-PAGETransmission Electron MicroscopyGene Therapy ResearchPreclinical Studies

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Author Spotlight: Advancing Gene Therapy Research with High-Titer Adeno-Associated Virus Vector Production

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