This publication shows the application of x-ray diffraction and differential scanning calorimetry as gold standards for investigating the solid-state of lipid-based excipients (LBEs). Understanding the solid-state alteration in LBEs and its effect on the performance of pharmaceutical products thereof is the key factor for manufacturing robust lipid-based dosage forms.
Salar-Behzadi, S., Corzo, C., Laggner, P. A Package of Established Analytical Tools to Investigate the Solid-State Alteration of Lipid-Based Excipients. J. Vis. Exp. (186), e63993, doi:10.3791/63993 (2022).