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ヒトCRISPR設計CAR-T細胞の製造

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Production of Human CRISPR-Engineered CAR-T Cells

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ヒトCRISPR設計CAR-T細胞の製造

11,686 Views

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06:33 min

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March 15, 2021

DOI:

10.3791/62299-v

DOI:

10.3791/62299-v

•

06:33 min

March 15, 2021

•

33 Views

Sangya Agarwal*^1,2, Nils Wellhausen*^1,2, Bruce L. Levine^1,2, Carl H. June^1,2

¹Center for Cellular Immunotherapies, Perelman School of Medicine,University of Pennsylvania, ²Parker Institute for Cancer Immunotherapy,University of Pennsylvania

Summary

ここでは、CRISPR Cas技術を用いてCAR-T細胞を改変する原発ヒトT細胞における遺伝子編集プロトコルを紹介する。

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