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A High-Throughput Electrochemiluminescence 7-Plex Assay Simultaneously Screening for Type 1 Diabetes and Multiple Autoimmune Diseases
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May 29, 2020
DOI:
1Barbara Davis Center for Diabetes,University of Colorado School of Medicine, 2Department of Endocrinology, Beijing Hospital, National Center of Gerontology; Institute of Geriatric Medicine,Chinese Academy of Medical Sciences, 3Department of endocrinology, Guangzhou First People’s Hospital, School of Medicine,South China University of Technology
Summary
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We model a simple multiplexed ECL assay that combines 7 autoantibody assays together. The assay is capable of screening for T1D and multiple other autoimmune diseases, simultaneously, including celiac disease, autoimmune thyroid disease, and autoimmune polyglandular syndrome 1.
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Jia, X., He, L., Gu, Y., High, H., Yu, L. A High-Throughput Electrochemiluminescence 7-Plex Assay Simultaneously Screening for Type 1 Diabetes and Multiple Autoimmune Diseases. J. Vis. Exp. (159), e61160, doi:10.3791/61160 (2020).
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