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Journal / Immunology and Infection / 微生物通过微血管内皮细胞对血脑屏障渗透性分析…
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Immunology and Infection

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JoVE Journal Immunology and Infection
微生物通过微血管内皮细胞对血脑屏障渗透性分析
 
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微生物通过微血管内皮细胞对血脑屏障渗透性分析

Article DOI: 10.3791/60692-v • 06:26 min • February 14th, 2020
February 14th, 2020 •
1, 1, 1, 1
1Institute of Physiological Chemistry, Martin Luther University Halle-Wittenberg

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人类血脑屏障选择性地防止亲水分子和病原体渗透到大脑中。几种疾病，包括脑膜炎和术后精神错乱，与血脑屏障的渗透性增加有关。在这里，我们描述了一个内皮细胞培养模型，以测试通过微生物遍历的屏障渗透性。

Tags

免疫学和感染，问题156，细菌横行，血脑屏障，细胞粘附，化合物筛选，内皮细胞，炎症，脑膜炎，细胞渗透性，术后精神错乱，紧密结，转染人类脑微血管内皮细胞
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